Combination therapies funding call
Our new £2 million funding call welcomes both preclinical and clinical applications from around the globe to test rationally designed combinations of two or more drugs for disease modification in Parkinson’s.
We will be accepting expressions of interest for funding from Wednesday 1 October until Monday 24 November.
Q&A Sessions
As this is a new funding call, we will be hosting two question and answer (Q&A) sessions via Zoom to give prospective applicants an overview of the different types of combinations, an update from a workshop hosted earlier this year and to answer any questions applicants might have.
These sessions will be held on:
• Thursday 16 October 2025, 10am (BST)
• Monday 3 November 2025, 4pm (GMT)
Our funding remit
For preclinical projects, applicants can request up to £300,000. Projects that are likely to lead to clinical trials in people with Parkinson’s within five years will be prioritised.
For clinical applications, applicants can request in the region of £1 million to fund clinical trials or sub-studies of trials evaluating drug combinations in people with Parkinson’s.
We fund internationally and accept applications from academic institutions and commercial entities. However, the costs in commercial applications should be justified and equivalent to academic costs where possible.
What is a combination therapy?
For the purposes of this funding call, when talking about a combination therapy, Cure Parkinson’s is referring to a treatment that involves two or more active agents to achieve a desired biological effect. Although we recognise that combination therapies can involve interventional treatments, like diet and exercise, in this instance, we are solely referring to combinations of drugs. Combinations can be novel, meaning they have not been tested together before, or repurposed/repositioned, meaning that the combination of agents is already licensed for another disease indication.
How to apply
To be considered for funding, please complete the following forms which can be accessed at the bottom of this page:
- an expression of interest form
- a drug CV – one for each agent you intend to investigate
- a commercial entity form (if applicable)
Completed forms should be emailed to research@cureparkinsons.org.uk by 11.59pm (GMT) Monday 24 November 2025.
Following internal review, those most closely aligned with the goals of the funding call will be invited to submit a full application.
Application process
Upon receipt of expressions of interest, members of Cure Parkinson’s Research Team, along with the chair of the independent panel, will review applications for their:
- appropriateness to Cure Parkinson’s funding remit
- scientific rationale and supporting data for the drug combinations proposed
- estimated budget and value for money
- evidence of involvement from people with Parkinson’s, or a clear plan on how to involve them
Those most closely aligned with the above criteria will be invited to submit a full application, to be received by Cure Parkinson’s by Monday 26 January 2026, before being sent for external peer review.
Full applications and feedback from peer reviewers will be discussed at an independent panel meeting. During the meeting, the panel will evaluate each application, with fundable proposals recommended to the Cure Parkinson’s trustees for potential funding, up to a total value of £2 million.
Please note, only full applications that have been invited for submission will be sent out to external peer review and further considered for funding by our independent panel.
All successful and unsuccessful applicants will be notified by the chair of the panel and/or a suitable Cure Parkinson’s representative.
Please review the guidance for applicants document below for more information about the funding call, evaluation criteria and how to apply. If you have any questions, please email the Research Team.
To be considered for funding, please email a completed expression of interest form, drug CV (one for each agent) and commercial entity form to research@cureparkinsons.org.uk by 11:59pm (GMT) Monday 24 November 2025.
