Rallying to the Challenge 2023: recorded to watch again
Rallying to the Challenge is a meeting designed for and by people with Parkinson’s, advocates and care partners to explore how the Parkinson’s community can impact and accelerate research.
Each year the meeting takes an aspect of Parkinson’s research and discusses how people living with the condition can support and influence work in this area.
This year’s theme was: What do we mean by “pathophysiological mechanisms to therapeutics?” which mirrored the science symposium Grand Challenges in Parkinson’s Disease at Van Andel Institute, U.S.
You can now re-watch presentations from this year’s Rallying to the Challenge meeting:
Day One
What do we mean by “Pathophysiological Mechanisms to Therapeutics”? – Dr. Simon Stott
Protein Pathologies 1: Alpha-synuclein, what is it, how can we detect it? – Dr Eraz Anis and Dr Saima Zameer (VAI)
A-synuclein seeding assay: what is it and how can it support clinical trials? – Anaya Navangul
Protein pathologies 2: Tau pathology and its impact in Parkinson’s – Dr Alysa Kasem (VAI)
What is better than L’dopa? – Dr Soania Mathur
Defining the biology of Parkinson’s – Martijn Muller
Why is a staging system for Parkinson’s so urgently needed? – Gary Rafaloff and Katie Kopil
Communications implications and use of language of a new staging system – Claire Bale
Day Two
A review of the stages of clinical trials – Sean Hindley
Therapeutic development 1: an overview of disease-modifying trials – Gary Rafaloff
Therapeutic development 2: Lysosomal function overview, ambroxol – Rosie Fuest and Helen Matthews
Therapeutic development 3: Could Prasinezumab be reducing motor progression in the PASADENA Open-Label Extension – Dr Patrik Brundin and Matthew May
Therapeutic development 4: The challenges of developing combination therapies – Dr Sonia Gandi
