Neurotrophic factors (or nerve growth factors) are small proteins that enhance the growth and survival potential of neurons. They play important roles in both the development and survival of neurons. In laboratory testing, they have demonstrated that they are capable of regrowing damaged neurons.

In Parkinson’s research, neurotrophic factors are of particular interest for their potential protection of dopamine-producing neurons and motor behaviour recovery.

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Latest updates

Neurotrophic Factor GDF5 – an alternative to GDNF?

Neurotrophic factors are small protein that are naturally produced in the brain to help nurture and protect nerve cells (neurons). Cure Parkinson's is...

Nerve growth factors and Parkinson’s

Nerve growth or neurotrophic factors such as CDNF and GDNF are proteins that support neurons and encourage their growth and survival during development. There...

Documentary: ‘The Parkinson’s Drug Trial: A Miracle Cure?’

This award winning documentary was first broadcast in 2019 and features trial participants, including our late co-founder Tom Isaacs, in a cutting-edge drug trial...

GDNF – A new chapter

We welcome the news of further investment in GDNF (Glial Cell-Line Derived Neurotrophic Factor) by Parkinson’s UK.

‘AskBio’ acquires BNB and GDNF gene therapy trials

BNB and AskBio have joined forces to expand a gene therapy programme for Parkinson's