What does a cure for Parkinson’s look like and how can it be achieved?

We believe that there will be three steps to curing Parkinson’s, steps that slow, stop and reverse the condition.

1. Stopping Parkinson’s from progressing – Parkinson’s is a progressive condition, which means that gradually, over time the symptoms get worse. Therefore, the first step in correcting the disease is to identify agents that will slow or stop the progression of the condition.

2. Restoring lost function  – Once the disease progression is halted, it will be important to replace the lost cells and their function. Cell replacement therapies represent a viable approach here.  

3. Protecting the brain cells affected by Parkinson’s – once the progression of the condition has been slowed, it will be important to support and protect surviving cells and provide a nurturing environment for restorative therapies. This will involve identifying neuroprotective treatments.

Cure Parkinson’s is supporting research in all three of these areas. Through our International Linked Clinical Trials (iLCT) programme, we have clinical studies evaluating all aspects of a cure, bringing novel therapies to the clinic for the Parkinson’s community.

At first glance the task ahead of us seems insurmountable, but there is already a huge amount of research being conducted at the clinical level across all three components of a cure for Parkinson’s. And through clinical trials supported by Cure Parkinson’s we are seeing the first signs of potentially disease modifying therapies. It is a very exciting time for Parkinson’s research.

Dr Simon Stott, Deputy Director of Research, Cure Parkinson’s