Evidence from Johns Hopkins Medicine showed that alpha-synuclein began building where the vagus nerve connected to the gut and continued to spread through all parts of the brain. It also demonstrated that blocking the transmission route could be key to preventing the physical and cognitive manifestations of Parkinson’s.
These findings provide further proof of the gut’s role in Parkinson’s, and gives us a model to study the disease’s progression from the start. This is an exciting discovery for the field and presents a target for early intervention in the disease.Professor Ted Dawson, M.D. Ph.D, Director of Johns Hopkins Institute for Cell Engineering, Professor of Neurology at the Johns Hopkins University School of Medicine and a member of CP’s International Linked Clinical Trials committee